The health and safety of our employees, patients, customers and communities is our top priority. Learn more about how Inspire treats obstructive sleep apnea from inside the body with the click of a remote. Sign up for a live online event where you can learn and engage in real time with Inspire-trained doctors and Inspire patients.
Once you are ready to get started, you can set up a telemedicine or in-person appointment with an Inspire-trained doctor. Inspire is the only FDA approved obstructive sleep apnea treatment that works inside your body to treat the root cause of sleep apnea with just the click of a button. Inspire works inside your body while you sleep.
While you sleep, Inspire opens your airway, allowing you to breathe normally and sleep peacefully. Inspire treats the root cause of sleep apnea by applying gentle stimulation to key airway muscles during sleep, allowing you to breathe normally, and more importantly, sleep without a mask, hose, or machine.
Inspire is placed under the skin of the neck and chest during a short, outpatient procedure. Inspire was FDA approved in and has been proven both safe and effective in multiple clinical studies. It is the only FDA approved obstructive sleep apnea treatment that works inside the body with just the click of a button.
Inspire lets you sleep without a mask or hose. It works inside the body and is simply turned on and off with a press of a button. The Inspire remote fits in the palm of your hand and only requires 2 AAA batteries. Travel lightly and sleep anywhere, with just the click of a button.
An Inspire trained doctor will evaluate your overall health and sleep apnea history to decide if Inspire is right for you. Inspire is covered by most major insurance providers, including Medicare. Depending on your provider, insurance approval can take a few days or a few weeks.
Click here to learn more about insurance coverage for Inspire. Shortly after the procedure, head back to your doctor to turn Inspire on. Sign up for a free online educational event in your area where you can learn more about Inspire and speak with an Inspire user. Skip to content The health and safety of our employees, patients, customers and communities is our top priority.
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No mask. No hose. Just sleep. How it Works Inspire works inside your body while you sleep. Watch How it Works. Why Choose Inspire. Alternative to CPAP Inspire treats the root cause of sleep apnea by applying gentle stimulation to key airway muscles during sleep, allowing you to breathe normally, and more importantly, sleep without a mask, hose, or machine.
Outpatient Inspire is placed under the skin of the neck and chest during a short, outpatient procedure. A better fit for you and your nightstand. The Button Inspire lets you sleep without a mask or hose. Size A small remote that fits easily on your nightstand.
Patient Outcomes. Assessment and Eligibility.
Insurance Approval. Sleeping with Inspire.ActivInspire is a collaborative lesson delivery software for interactive displays. Known and loved by educators around the world, ActivInspire provides a vast suite of tools to create and deliver dynamic lessons. Teachers can easily import their existing resources, such as PowerPoint slides and PDFs, and embed multimedia files.
Encourage student collaboration at the front of the class with multi-touch functionality and unique engagement features like interactive math tools, Spotlight, and more. Teachers now have new ways to engage with fully customizable, interactive activities.
Teachers can quickly tailor each activity based on subject matter and invite multiple students to the front of the class to interact with full screen, multi-touch capability.
Lesson engagement is just a few clicks away. The myPromethean Resource Library provides ActivInspire users with access to over 30, free Flipcharts that have been created by teachers, for teachers. Teachers can easily search, filter, preview, and download Flipcharts — saving valuable lesson preparation time. Promethean is continually investing in and developing new ActivInspire training resources that can help you with effectively integrating ActivInspire lesson delivery software into your classroom.
Discover ActivInspire product tips, teaching ideas, technology trends, and more from Promethean. Yemen Zambia Zimbabwe Opt In Yes, contact me by electronic means so that I can receive educational materials and the latest news and information about events, products and services from Promethean, its affiliates and resellers.
Visit the Resource Library. Learn Promethean Training Hub Promethean is continually investing in and developing new ActivInspire training resources that can help you with effectively integrating ActivInspire lesson delivery software into your classroom. Yemen Zambia Zimbabwe.A breast cancer support group with over 30, members created for patients and caregivers living with metastatic breast cancer.
Find answers to common questions about metastatic breast cancer and join a breast cancer support group of individuals with similar experiences. Interested in learning more about metastatic breast cancer treatments? Learn about various treatments side effects, effectiveness, cost, interactions, read about other members experiences, tips, and more.
This group has given me so much hope! I used to be terrified, now I feel very positive and optimistic. It is so informative and all of us are in the same boat with different areas that are affected.
We keep each other going through hard times and sometimes even good times. It is the best support group that I have found. The sisters and brothers are wonderful This is a scary diseasebut many have lived a long time with it. We know what it's like to wonder what's going on - all the time : Sometimes, we really talk about the big issues here - disease, death, etc - but sometimes, we rant and rave about the ""little"" things too.
This is a safe place to say you hate everyone else for being healthy : I know, you don't hate them, and neither do I, but I am sure jealous sometimes!
Welcome new Inspirette. May you find all the information and encouragement you need, here. Looking for more metastatic breast cancer support and resources? Connect with advanced breast cancer patients and caregivers for support on metastatic breast cancer, immunotherapy, genetic testing, and clinical trials. Hiding this post will prevent you from seeing it on your home page, community pages and activity summary. Are you sure you want to do this? I was on Ibrance and Letrozole for 15 months.
Advanced Breast Cancer Support and Resources
In January I started on Fulvestrant and I am already seeing progression. They now want me to start on Ibrance alone. Has anyone else had this same regimen? However, I am wondering if trying Ibrance and Fulvestrant will work better. Thank you, any input is appreciated Read More. Hi, I had my first blood test done because of some small lumps found around both breasts. The rest were noted as normal. I have severe lower body inflammation a foot of colon removed in How many of you have lost your hair on Doxil and what was your experience Afinitor has made me anemic.
Currently taking 10 mg of Afinitor red blood platelets are 6. May need another one this coming week. Need to decide if I want to drop Dose or continue with blood transfusions has anyone experienced this Dear members, Many of us, including myself, have spent a good bit of time in hospitals, as a patient or a caregiver or both, and have ideas about how hospitals can improve.
Due to that pioneering research of doctors and scientists we now have our new immunotherapy. Took almost 25 years from the lab studies to clinic.Inspire strives to find better ways to connect patients to relevant clinical trials. The goals of our clinical trial program are to:. Inspire works with our partner organizations and clinical trial sponsors. We require that clinical trial sponsors meet the following criteria:.
Inspire recommends that all patients considering participation in a clinical trial discuss the information with their doctor. Your physician will be familiar with your medical history and can best evaluate the study criteria to determine if the clinical trial is appropriate for you. Inspire recognizes that the decision to participate in a clinical trial is a personal one and should be made only after careful consideration of the potential risks and benefits.
Inspire encourages patients to explore clinical trials as a treatment option and provides links to comprehensive resources that attempt to offer opportunities for patients to learn about all of the clinical trials being conducted for which they might be eligible.
Through its partners, Inspire provides general education about clinical trials, including what clinical trials are, how they are conducted, the types of trials available to individuals and common barriers to participation people experience in clinical trials.
We encourage our members to visit our partners' sites for more information. Once Inspire agrees to work with a clinical trial sponsor, we attempt to connect members who are interested in and qualified for the trial with the trial investigators. The process is completely opt-in for Inspire members.
No personally identifiable member information is shared with anyone outside of Inspire without the member's express permission. The process of connecting members with trial investigators involves three steps:. The process starts with the clinical trial sponsor providing Inspire with inclusion and exclusion criteria for the trial. We use the basic inclusion and exclusion criteria to determine which members to contact about the trial.
Basic inclusion and exclusion criteria include the condition being studied, the desired age range and gender of patients, and location of study sites. Using the basic inclusion and exclusion criteria, we send a message to members who we believe may be interested in the trial, subject to their preferences regarding such communication.
We do not contact members who have, by setting their message preferences accordingly, opted out of clinical trial notifications. The message we send provides a link to a qualification questionnaire which gives complete information about the trial along with questions the member can answer to determine if she may qualify.
For some clinical trials we may also publish information about the trial and a link to the qualification questionnaire in public areas of Inspire. Members who are not interested in the trial can simply ignore these communications. Members who are interested in the trial can visit the qualification questionnaire to learn more about the trial and see if they may qualify for it. The qualification questionnaire provides information and links for learning about the trial in depth, and a set of questions based on the trial's inclusion and exclusion criteria.
Members who are not interested in the trial can simply ignore the questionnaire. Members who are interested can complete the questionnaire to see if they may qualify. In the questionnaire we ask for contact information name, phone number and require that the member agree that if her answers suggest she may qualify for the trial, we may share her responses with the physicians and nurses conducting the trial also known as Principal Investigators or PIs.
Anyone who does not wish to share their responses with the PIs investigating the trial can simply opt not to fill out the questionnaire. Upon completing the questionnaire, if a member's responses indicate that she may qualify for the trial, we provide the member with contact information for the PI nearest to her. At the same time we notify that PI that a member who may qualify for the trial has completed the questionnaire.
The PI can then access a secure, password-protected, encrypted site on Inspire's servers to retrieve the member's contact information and questionnaire responses. In most cases we expect the PI to contact the member, but the member may contact the PI herself. We provide both the member and the PI with contact information to facilitate their getting in touch with each other. Once the PI and member are in touch, the PI will discuss the trial in depth with the member, inquire about additional inclusion and exclusion criteria, schedule an appointment for in-person screening, and perform any other steps necessary to ensure that the patient is fully informed about the trial and qualified to participate.
Inspire's policy on clinical trials Inspire strives to find better ways to connect patients to relevant clinical trials. The goals of our clinical trial program are to: Raise awareness of clinical trials Increase the number of patients who identify clinical trials as part of their review of care and treatment options Reduce the number of patients who get lost or overwhelmed by the search process Help our partners by providing a resource for clinical trials for their constituents Increase participation in clinical trials and help expedite the availability of better ways to prevent, diagnose and treat disease How we select clinical trials and studies Inspire works with our partner organizations and clinical trial sponsors.
We require that clinical trial sponsors meet the following criteria: The clinical trial or study must be scientifically rigorous and employ appropriate and meaningful outcomes The clinical trial or study must be approved by an Institutional Review Board IRB.Study record managers: refer to the Data Element Definitions if submitting registration or results information.
This is a Phase III, open-label, randomized, controlled, international study. For all randomized patients who discontinue study treatment, subsequent therapies with their start and end dates, as well as survival time after treatment discontinuation, will be documented at least monthly until death. Patients in the PC group who progress will not be allowed to cross over to rigosertib.
All patients in both treatment groups will be allowed, as medically justified, access to RBC and platelet transfusions and to growth factors granulocyte colony-stimulating factor G-CSFerythropoietin, and thrombopoietin. Other Name: ON Secondary Outcome Measures : Overall survival of patients with monosomy 7 chromosomal aberrations.
Overall survival is the time months from date of randomization to date of death or date last known to be alive at the time of date cut-off. Overall survival of patients with trisomy 8 chromosomal aberrations. Percent of patients with response according to IWG criteria. Scores of Quality of Life Questionnaire. Percent of patients with bone marrow blast response rate according to IWG criteria. Percent of patients with hematologic improvement HI erythroid, platelet and neutrophil responses according to IWG criteria.The World of Vala: Season 4, Episode 70: The Trial of the Mind
Safety Objective: Rigosertib population pharmacokinetics PK. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below.
For general information, Learn About Clinical Studies. Female patients of child-bearing potential and male patients with sexual partners of child-bearing potential who are unwilling to follow strict contraception requirements before entry and throughout the study, up to and including the day non-treatment follow-up period.
Examples of acceptable contraception methods include:. Hide glossary Glossary Study record managers: refer to the Data Element Definitions if submitting registration or results information.
Search for terms x. COVID is an emerging, rapidly evolving situation. Save this study. Warning You have reached the maximum number of saved studies Listing a study does not mean it has been evaluated by the U. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details. Last Update Posted : October 12, See Contacts and Locations. Study Description.Poultry farming pdf
Detailed Description:. The drugs used in the Physician's Choice arm should be used according to the recommendations, if clinically appropriate, provided in the corresponding Summary of Product Characteristics SmPC and Prescribing Information of these drugs.Applied early in the product development lifecycle, Altair Inspire accelerates the creation, optimization, and study of innovative, structurally efficient parts and assemblies through collaboration.
Inspire's award winning user experience for geometry creation and modification can be learned in just a few hours, and delivers dependable Altair solver power: Structural analysis with Altair SimSolid 's speed and accuracy - as independently validated by NAFEMS - provides the ability to analyze large assemblies and complex parts.
Dynamic motion simulation, including loads extraction, using the reliable multi-body systems analysis of Altair MotionSolve. The industry standard for structural efficiency, topology optimization by Altair OptiStructfor the generative design of practical, viable and manufacturable geometry. Inspire enables both simulation analysts and designers to perform what-if studies faster, easier, and above all earlier, encouraging collaboration and reducing product time to market.
Altair Inspire Overview Video. Create, modify, and de-feature solid models using Altair Inspire's modeling tools. Leverage the speed and accuracy of SimSolid to evaluate multiple variants. Altair Inspire offers a number of topology options including: optimization objectives, stress and displacement constraints, acceleration, gravity, and temperature loading conditions.
Design for additive manufacturing with overhang shape controls to help reduce overhangs to create more self-supporting structures. Investigate linear static and normal modes analysis on a model and visualize displacement, factor of safety, percent of yield, tension and compression, von Mises stress, and major principal stress.
Multiple assembly configurations can be created. These configurations can then be used to evaluate various design scenarios and the resulting concepts. Interested in giving the solidThinking Suite a test run? Request access to a free day trial of the solidThinking Suite. Want to explore a purchase of the solidThinking suite for yourself or company? Request a free, no obligation quote.What is the best cleaner to use to remove nicotine from walls
Subscribe to join our Newsletter Learn about product training, news, events, and more. Coronavirus Preparedness Statement. Read More. What is Altair Inspire? Why Altair Inspire? Create, modify, and defeature solid models quickly, use PolyNURBS to create free-form smooth geometry, and study multiple assembly configurations. Optimize for Manufacturability. Arrive at the ideal design direction extremely early in the process: topology optimization is based on physics and observes manufacturing process constraints.
Simulate at the Speed of Design. Experience an interactive engineering design environment for rapid design exploration and product creation, without the need to invest in new computer hardware. Altair Inspire Features. Motion Analysis. Overhang Shape Controls. Profile Editor. Customer Story Alstom Learn More. Request a Trial Interested in giving the solidThinking Suite a test run?
Request a Trial. Request a Quote Want to explore a purchase of the solidThinking suite for yourself or company? Request a Quote. Ask a Question Have a question about the solidThinking suite?We know that this is an especially worrying time for people with cancer and their family and friends. We have separate information about coronavirus and cancer.
Please read that information alongside this page. We will update that information as guidance changes. Read about coronavirus and cancer. This trial is looking at rigosertib for people who have already had treatment for their myelodysplastic syndrome MDS.
This causes a drop in the normal blood cells. Treatment for MDS can include chemotherapy such as azacitidine and a stem cell transplant. Unfortunately sometimes these treatments do not work. And the MDS continues to get worse or comes back after treatment.Kara sevda final
Researchers want to see if rigosertib can help people in this situation. The following bullet points list the entry conditions for this trial.Ego lm2135sp
Talk to your doctor or the trial team if you are unsure about any of these. They will be able to advise you. You may be able to join this trial if all of the following apply. You have myelodysplastic syndrome MDS and you are in one of the following situations:. This is a phase 3 trial. The researchers need people to join. It is a randomised trial. People taking part are put into 1 of 2 treatment groups by a computer. Neither you or your doctor can choose which group you are in.
The 2 groups are:. You have a pump attached to the central line that delivers the rigosertib continuously. You have it over 3 days. If you are not having rigosertib your doctor will talk to you about what other treatment might be best for you. These are taken when you have a bone marrow test and blood tests done as part of your routine care.
These samples are used to find out more about MDS. They will also use the blood samples to find what happens to rigosertib in the body. You can still take part in the trial. You fill in a questionnaire before you start treatment, then every 4 weeks during treatment and at the end of treatment. The questions will ask about any symptoms you have and how you are feeling.
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